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Comments:	: was discovered by Glaxo Wellcome now GlaxoSmithKline under a partnership between Glaxo and ICOS to develop new drugs that began in August In the Bothell Washington biotechnology company ICOS Corporation began studying compound IC a phosphodiesterase typePDE enzyme inhibitor In Pfizer scientists discovered that sildenafil which also inhibits the PDE enzyme caused penile erection in men participating in a clinical study of a heart medicine Although ICOS scientists weretesting compound IC for treating ED they recognized its potential usefulness for treating that disorder Soon in ICOS received a patent for compound IC structurally unlike sildenafil and vardenafil and Phaseclinical trials began in , <a href=" http://www.nanj.org/nnjrscwiki/nanj.php?cialis_side_effects">cialis overdose</a>, 347,
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